MRSA infections

MRSA infections are fairly common in the hospitalized patients.

Treatment of MRSA Skin and Soft Tissue Infections

Common Medications Used: 

PO Medications: Clindamycin for susceptible strains, TMP/SMX, Doxycycline. You can give these IV too.

IV medications: Vancomycin 20 mg/kg IV q 12h, Ceftaroline 600 mg IV q 12h, Daptomycin 4 mg/kg or 6 mg/kg

-Resistance to quinolones and Tetracyclines can develop on therapy, so don’t use them.

-Do not prescribe Rifampin by itself

-Mupirocin nasal ointment can be used to decrease nasal colonization but it is not commonly used or needed

-Nose picking can increase nasal MRSA