Renal tubular acidosis (RTA) occurs when the kidneys do not remove acids from the blood into the urine as they should.
Type 3 RTA is rarely used as a classification because it’s thought to be a combination of type 1 and type 2 RTA. [3=1+2]
We need to be thorough with these 3 types of Renal Tubular Acidosis.
| RTA type | 2 | 4 | 1 |
| Location | Proximal | Hyperkalemic | Distal |
| Defect | HCO3 reabsorption | H,K excretion | H excretion |
| Hypokalemia | HyperKalemia | Hypokalemia | |
| Stones | +/- | + | |
| pH | >5.5 | <5.5 | |
| Conditions | |||
| Tip to remember | TWO TOMAF | HK and HD | ONE OPRASSH |
| Topiramate | Hypoaldosteronism | Obstruction [distal] | |
| Osteomalacia | Diabetes Mellitus | PBC | |
| Multiple Myeloma | RA | ||
| Acetazolamide/Zonisamide | Amphotericin | ||
| Fanconi Syndrome | SLE | ||
| Sjogren’s | |||
| Hyperthyroidism | |||
